Proton MR spectroscopic imaging (MRSI) metabolite ratios in human brain: calculating repeatability when measurement error is proportional to the mean
نویسندگان
چکیده
Introduction: In vivo proton magnetic resonance spectroscopic imaging (MRSI) has a proven track record as a research tool and shows clinical promise in a range of diseases including brain tumours [1, 2], stroke [3, 4], epilepsy [5, 6] and multiple sclerosis [7, 8]. To enable reliable clinical (diagnostic and longitudinal) use, the repeatability of the technique must be quantified. Whilst studies have quantified repeatability [9–16], it is imperative that the procedure is repeated for all scanners and institutions so as to account for differences in hardware, pulse sequences, etc. A study was, therefore, undertaken to quantify repeatability at our own institution.
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